Our central question is Kant’s: Whether such a thing as metaphysics is even possible at all. After briefly considering Kant's answer (week 1), we examine verificationist-inspired scepticism about the possibility of metaphysics (weeks 2–4). These sceptical challenges characterised metaphysics and science as wholly separate disciplines. We then consider the upset caused by Quine (weeks 5–8), who paved the way for a brand of metaphysics which styled itself as continuous with empirical science. We will close with two rather different reactions to the (neo-)Quinean orthodoxy (weeks 9–10), both of which claim to offer ways to continue with metaphysics, but may involve giving up on it altogether.