This module will explore the neurobiological underpinnings of neurodegenerative diseases. It will focus on the anatomical and functional alterations in a variety of degenerative neurological disorders. Emphasis will be put on recent research into understanding the molecular and cellular mechanisms of disease and, when applicable, how this might lead (or has led) to new therapeutic venues. Students will be encouraged to use the knowledge of functional neuroanatomy, neurophysiology and molecular and cellular neurobiology acquired as part of their Neuroscience degree course in a synoptic manner, to understand basic neuropathology.