CARD: Institute of Cardiovascular Science
The aim of this module is to provide an understanding of how evidence that guides clinical practice is generated (from pre-clinical to clinical studies) as well as develop a systematic approach to assessing evidence and applying it to real life clinical scenarios. This integrative module will reinforce knowledge on cardiovascular disease pathophysiology delivered in the Heart and Circulation module and build on understanding of clinical research methodology and appraisal from the Year 2 Use of Evidence and Use of Medicines modules. There will be a particular focus on how new therapeutic interventions for cardiovascular disease are developed, how relevant evidence is generated and on appraisal of interventional studies.

This module will be organised around clinical case scenarios that will cover topics such as hypertension, heart failure, diabetes, obesity, coronary artery disease and congenital heart disease. In addition, focused workshop(s) will be held to help the student to identify and characterise current & novel treatment options for patients with cardiovascular diseases and cover principals of how data analysis and statistics for research are applied to assess the action of these drugs. Learning will be through seminar-style lectures, tutorials, class discussions on a case study that students will have written-up as a report, attending a clinic in one/two of the above specialties.
Students will choose from a range of cardiovascular topics that can be laboratory based, involve data collection and/or analysis of retrospective or ongoing clinical research or involve gene annotation. Where appropriate, the supervisor will have obtained ethical approval for the work, but students will be expected to write a research plan pointing out ethical and statistical issues. Deadlines for choosing research projects and writing ethics applications will be set early in the 1st term.